Heparin reversal with protamine sulfate after Percutaneous Hepatic Perfusion (PHP): is less more?
Abstract Purpose Percutaneous hepatic perfusion (PHP) is a palliative intraarterial therapy for unresectable hepatic malignancies.During PHP, high-dose melphalan is infused via the hepatic artery to saturate tumor in the liver with the chemotherapeutic substance.The venous hepatic blood is filtered by an extracorporeal melphalan specific filtration